Ontario Health Study

2024

Azab, S., M., Doiron, D., Schulze, K. M., et al. (2024). Exposure to air pollutants and subclinical carotid atherosclerosis measured by magnetic resonance imaging: A cross-sectional analysis. PLoS ONE, 19(10), e0309912. https://doi.org/10.1371/journal.pone.0309912

O’Sullivan, D. E., Ruan, Y., Farah, E., et al., (2024). Risk factors for early-onset colorectal cancer: A Canadian prospective cohort study. Cancer Epidemiology, 91, 102578. https://doi.org/10.1016/j.canep.2024.102578

Basten, M., Pan, K.-Y., van Tuijl, L. A., et al. (2024). Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis. International Journal of Cancer, 154(10). https://doi.org/10.1002/ijc.34852

Verschoor, C. P., Theou, O., Ma, J., et al. (2024). Age- and sex-specific associations of frailty with mortality and healthcare utilization in community-dwelling adults from Ontario, Canada. BMC Geriatrics, 24, 223. https://doi.org/10.1186/s12877-024-04842-4

Pan, K.-Y., van Tuijl, L., Basten, M., et al. (2024). The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: An individual participant data meta-analysis. Psychological Medicine. https://doi.org/10.1017/S0033291724000850

O’Sullivan, D. E., Ruan, Y., Farah, E., et al. (2024). Risk factors for early-onset colorectal cancer: A Canadian prospective cohort study. Cancer Epidemiology. https://doi.org/10.1016/j.canep.2024.102578

Stutheit-Zhao, E. Y., Sanz-Garcia, E., et al. (2024). Early changes in tumor-naive cell-free methylomes and fragmentomes predict outcomes in pembrolizumab-treated solid tumors. Cancer Discovery, 14(6), 1048–1063. https://doi.org/10.1158/2159-8290.CD-23-1060

Vasiliadis, H. M., Spagnolo, J., Fleury, M.-J., et al. (2024). Factors associated with mental health service use during the pandemic: Initiation and barriers. International Journal of Social Psychiatry, 70(1), 59–69. https://doi.org/10.1177/00207640231194489

Vasiliadis, H. M., Spagnolo, J., Bartram, M., et al. (2024). Factors associated with change in moderate or severe symptoms of anxiety and depression in community-living adults and older adults during the COVID-19 pandemic. Canadian Journal of Public Health, 115(2), 230–243. https://doi.org/10.17269/s41997-023-00832-y

 

2023

O’Sullivan, D. E., Hillier, T. W. R., Brenner, D. R., et al. (2023). Time spent in the sun and the risk of developing non-Hodgkin lymphoma: A Canadian cohort study. Cancer Causes & Control, 34(9), 791–799. https://doi.org/10.1007/s10552-023-01719-6

Darvishian, M., Moustaqim-Barrette, A., Awadalla, P., et al. (2023). Provincial variation in colorectal cancer screening adherence in Canada: Evidence from the Canadian Partnership for Tomorrow’s Health. Frontiers in Oncology, 13, 1113907. https://doi.org/10.3389/fonc.2023.1113907

Danieli, C., Moura, C. S., Pilote, L., et al. (2023). Importance of accounting for timing of time-varying exposures in association studies: Hydrochlorothiazide and non-melanoma skin cancer. Pharmacoepidemiology and Drug Safety, 32(12), 1411–1420. https://doi.org/10.1002/pds.5674

van Tuijl, L. A., Basten, M., Pan, K.-Y., et al. (2023). Depression, anxiety, and the risk of cancer: An individual participant data meta-analysis. Cancer, 129(20), 3287–3299. https://doi.org/10.1002/cncr.34853

Murphy, T. J., Swail, H., Jain, J., et al. (2023). The evolution of SARS-CoV-2 seroprevalence in Canada: A time-series study, 2020–2023. CMAJ, 195(31), E1030–E1037. https://doi.org/10.1503/cmaj.230249

Kirsh, V. A., Skead, K., McDonald, K., et al. (2023). Cohort profile: The Ontario Health Study (OHS). International Journal of Epidemiology, 52(2), e137-151. https://doi.org/10.1093/ije/dyac156

Wang, Y., Namba, S., Lopera, E., et al. (2023). Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts. Cell Genomics, 3(1), 100241. https://doi.org/10.1016/j.xgen.2022.100241

Vasiliadis H. M., Spagnolo J., Fleury M.J., et al. (2023). Mental health service use and associated predisposing, enabling and need factors in community living adults and older adults across Canada. BMC Health Services Research, 23, 357. https://doi.org/10.1186/s12913-023-09335-5

Abbatangelo CL, Lona Durazo F, Wendt FR, et al. (2023). From Genetic Association to Forensic Prediction: Computational Methods and Tools for Identifying Phenotypically Informative Single Nucleotide Polymorphisms. Forensic Genomics, 3(2), 47-68. https://doi.org/10.1089/forensic.2023.0006

 

2022

Urquhart, R., Awadalla, P., Bhatti, P., et al. (2022). Harnessing the power of data linkage to enrich the cancer research ecosystem in Canada. International Journal of Population Data Science, 7(3), 1950. https://doi.org/10.23889/ijpds.v7i3.1950

Sud, M., Sivaswamy, A., Chu, A., et al. (2022). Population-based recalibration of the Framingham risk score and pooled cohort equations. Journal of the American College of Cardiology, 80(14), 1330–1342. https://doi.org/10.1016/j.jacc.2022.07.026

Zhou, W., Kanai, M., Wu, K. H., et al. (2022). Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. Cell Genomics, 2(10), 100192. https://doi.org/10.1016/j.xgen.2022.100192

Chen, S., Petricca, J., Ye, W. et al. (2022). The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors. Nature Communications, 13, 6467. https://doi.org/10.1038/s41467-022-34012-2

Xu, C., Nery, P. B., Wiefals, C., et al. (2022). Negative Association of Smoking History With Clinically Manifest Cardiac Sarcoidosis: A Case-Control Study. CJC Open, 4(9), 756-762. https://doi.org/10.1016/j.cjco.2022.06.001

Lona-Durazo, F., Thakur, R., Pairo-Castineira, E., et al. (2022). Investigating the genetic architecture of eye colour in a Canadian cohort. iScience, 25(6), 104485. https://doi.org/10.1016/j.isci.2022.104485

Murphy, R.A., Darvishian, M., Qi, J., et al. (2022). Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath). Cancer Causes & Control, 33, 913-918. https://doi.org/10.1007/s10552-022-01566-x

Anand, S. S., Friedrich, M. G., Lee, D. S., et al. (2022). Evaluation of Adiposity and Cognitive Function in Adults. JAMA Network Open, 5(2), e2146324. https://doi:10.1001/jamanetworkopen.2021.46324

Luu, J. M., Gebhard, C., Ramasundarahettige, C., et al. (2022). Normal sex and age-specific parameters in a multi-ethnic population: a cardiovascular magnetic resonance study of the Canadian Alliance for Healthy Hearts and Minds cohort. Journal of Cardiovascular Magnetic Resonance, 24, 2. https://doi.org/10.1186/s12968-021-00819-z

 

2021

Zhang, Z., Wang, J., Kwong, J. C., et al. (2021). Long-term exposure to air pollution and mortality in a prospective cohort: The Ontario Health Study. Environment International, 154, 106570. https://doi.org/10.1016/j.envint.2021.106570

Luu, J. M., Sergeant, A. K., Anand, S. S., et al. (2021). The impact of reporting magnetic resonance imaging incidental findings in the Canadian alliance for healthy hearts and minds cohort. BMC Medica Ethics, 22(1), 145. https://doi.org/10.1186/s12910-021-00706-3

Pader, J., Basmadjian, R. B., O’Sullivan, D. E., et al. (2021). Examining the etiology of early-onset breast cancer in the Canadian Partnership for Tomorrow’s Health (CanPath). Cancer Causes & Control, 32, 1117–1128. https://doi.org/10.1007/s10552-021-01460-y

van Tuijl, L. A., Voogd, A. C., de Graeff, A., et al. (2021). Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses. Brain and Behavior, 11, e2340. https://doi.org/10.1002/brb3.2340

Durrani, R., Friedrich, M. G., Schulze, K. M., et al. (2021). Effect of cognitive reserve on the association of vascular brain injury with cognition: Analysis of the PURE and CAHHM studies. Neurology, 97(17). https://doi.org/10.1212/WNL.0000000000012765

Lona-Durazo, F., Mendes, M., Thakur, R., et al. (2021). A large Canadian cohort provides insights into the genetic architecture of human hair colour. Communications Biology, 4, 1253. https://doi.org/10.1038/s42003-021-02764-0

Gerstein, H. C., Smith, E. E., Ramasundarahettige, C., et al. (2021). Diabetes, brain infarcts, cognition, and small vessels in the Canadian Alliance for Healthy Hearts and Minds Study. Journal of Clinical Endocrinology & Metabolism, 106(2), e891–e898. https://doi.org/10.1210/clinem/dgaa815

 

2020

Anand, S. S., Friedrich, M. G., Desai, D., et al. (2020). Reduced cognitive assessment scores among individuals with magnetic resonance imaging–detected vascular brain injury. Stroke, 51(4). https://doi.org/10.1161/STROKEAHA.119.028179

Hall, K. A., Singh, M., Mukherjee, S., & Palmer, L. J. (2020). Physical activity is associated with reduced prevalence of self-reported obstructive sleep apnea in a large, general population cohort study. Journal of Clinical Sleep Medicine, 16(7), 1179–1187. https://doi.org/10.5664/jcsm.8456

Singh, M., Hall, K. A., Reynolds, A., et al. (2020). The relationship of sleep duration with ethnicity and chronic disease in a Canadian general population cohort. Nature and Science of Sleep, 12, 239–251. https://doi.org/10.2147/NSS.S226834

Hall, R. E., et al. (2020). The Canadian Alliance for Healthy Hearts and Minds: How well does it reflect the Canadian population? CJC Open, 2(6). https://doi.org/10.1016/j.cjco.2020.07.013

 

2019

Fortier, I., Dragieva, N., Saliba, M., et al. (2019). Harmonization of the Health and Risk Factor Questionnaire data of the Canadian Partnership for Tomorrow Project: A descriptive analysis. CMAJ Open, 7(2), E272–E282. https://doi.org/10.9778/cmajo.20180062

 

2018

de Souza, R., Gauvin, L., Williams, N., et al. Environmental health assessment of communities across Canada: contextual factors study of the Canadian Alliance for Healthy Hearts and Minds. Cities & Health, 2(2), 163-180. https://doi.org/10.1080/23748834.2018.1548071

Kleiderman, E., Pack, A., Borry, P., et al. (2018). The author who wasn’t there? Fairness and attribution in publications following access to population biobanks. PLOS ONE, 13(3), e0194997. https://doi.org/10.1371/journal.pone.0194997

Dummer, T. J. B., Awadalla, P., Boileau, C., et al. (2018). The Canadian Partnership for Tomorrow Project: A pan-Canadian platform for research on chronic disease prevention. CMAJ, 190(23), E710–E717. https://doi.org/10.1503/cmaj.170292

 

2017

Drucker, A. M., Qureshi, A. A., Dummer, T. J. B., et al. (2017). Atopic dermatitis and risk of hypertension, type 2 diabetes, myocardial infarction and stroke in a cross-sectional analysis from the Canadian Partnership for Tomorrow Project. British Journal of Dermatology, 177(4), 1043–1051. https://doi.org/10.1111/bjd.15727

 

2016

Grace, S. L., Tan, Y., Cribbie, R. A., et al. (2016). The mental health status of ethnocultural minorities in Ontario and their mental health care. BMC Psychiatry, 16, 47. https://doi.org/10.1186/s12888-016-0759-z

Anand, S. S., Tu, J. V., Awadalla, P., et al. (2016). Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) – A pan-Canadian cohort study. BMC Public Health, 16, 650. https://doi.org/10.1186/s12889-016-3310-8

 

2015

Kardan, O., Gozdyra, P., Misic, B., et al. (2015). Neighborhood greenspace and health in a large urban center. Scientific Reports, 5, 11610. https://doi.org/10.1038/srep11610

 

2010

Fortier, I., Burton, P. R., Robson, P. J., et al. (2010). Quality, quantity and harmony: The DataSHaPER approach to integrating data across bioclinical studies. International Journal of Epidemiology, 39(5), 1383–1393. https://doi.org/10.1093/ije/dyq139

Borugian, M. J., Robson, P., Fortier, I., et al. (2010). The Canadian Partnership for Tomorrow Project: Building a pan-Canadian research platform for disease prevention. CMAJ, 182(11), 1197–1201. https://doi.org/10.1503/cmaj.091540